Nr3c2 | nuclear receptor subfamily 3, group C, member 2

GeneMGI:99459Synonyms: mineralocorticoid receptor, Mlr, +2 more

Physiological systems

20 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Behavior/neurological Mortality/aging

18 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Viability data
Body weight measurements
Embryo imaging data
Gene metrics:3Significant phenotypes
3Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased startle reflex1 supporting datasetNr3c2Nr3c2heterozygoteEarly adult2.31x10-5 
preweaning lethality, incomplete penetrance1 supporting datasetNr3c2Nr3c2homozygoteEarly adultN/A * 
preweaning lethality, complete penetrance1 supporting datasetNr3c2Nr3c2homozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Nr3c2tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
Nr3c2tm1e(EUCOMM)HmguTargeted, non-conditional allelees cell
Nr3c2tm1e(EUCOMM)WtsiTargeted, non-conditional allelees cell

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